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Barbara D. Boyan, Ph.D.

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Barbara D. Boyan, Ph.D.

Barbara D. Boyan, Ph.D.

Dean
Phone: (804) 828-3925
Fax: (804) 828-9866
Email: bdboyan@vcu.edu

Address
Virginia Commonwealth University
School of Engineering
West Hall, Room 331A
601 West Main Street
P.O. Box 843068
Richmond, Virginia 23284-3068

Education

  • B.A., biology, Rice University, 1970
  • M.A., comparative biochemistry and physiology, Rice University, 1974
  • Ph.D., comparative biochemistry and physiology, Rice University, 1975

Professional societies

Experience

  • Associate Dean for Research and Innovation in the College of Engineering at Georgia Institute of Technology
  • Professor and Price Gilbert, Jr. Chair in Tissue Engineering in the Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory University
  • Deputy Director of Research at Georgia Tech and at the Emory Center for the Engineering of Living Tissues at the Georgia Institute of Technology
  • Professor and Vice Chair for Research in the Department of Orthopaedics at the University of Texas Health Science Center at San Antonio
  • Co-founder of Osteobiologics, Inc.
  • Founder and Chief Scientific Officer of SpherIngenics, Inc.
  • Member, Board of Directors, ArthroCare Corporation and Carticept Medical, Inc.

Research topics

  • Cell and tissue engineering
  • Response of cells to biomaterials
  • Mechanisms of action of hormones and growth factors in cartilage and bone
  • Normal and pathological calcification
  • Stem cell delivery technologies

Selected patents

  • Calcium Binding Proteolipid Compositions and Methods (Pat. No . 6444446 )
  • Multi-Phase Bioerodible Implant/ Carrier and Method of Manufacturing and Using Same (Pat. No. 5,607,474)
  • Process of Making a Resorbable Implantation Device (Pat. No. 5,397,572)
  • Biodegradable Implant for Fracture Nonunions (Pat. No. 5,492,697)

Selected publications

  • Hermann CD, Lawrence K, Olivares-Navarrete R, Williams JK, Guldberg RE, Boyan
    BD, Schwartz Z. Rapid re-synostosis following suturectomy in pediatric mice is
    age and location dependent. Bone. 2013 Mar;53(1):284-93. doi:
    10.1016/j.bone.2012.11.019. Epub 2012 Nov 28. PubMed PMID: 23201269.
  • Coleman RM, Schwartz Z, Boyan BD, Guldberg RE. The therapeutic effect of bone
    marrow-derived stem cell implantation after epiphyseal plate injury is abrogated
    by chondrogenic predifferentiation. Tissue Eng Part A. 2013 Feb;19(3-4):475-83.
    doi: 10.1089/ten.TEA.2012.0125. Epub 2012 Oct 10. PubMed PMID: 22920855.
  • Nicolella DP, O Connor MJ, Enoka RM, Boyan BD, Hart DA, Resnick E, Berkley KJ,
    Sluka KA, Kwoh CK, Tosi LL, Coutts RD, Havill LM, Kohrt WM. Mechanical
    contributors to sex differences in idiopathic knee osteoarthritis. Biol Sex
    Differ. 2012 Dec 23;3(1):28. [Epub ahead of print] PubMed PMID: 23259740.
  • Sluka KA, Berkley KJ, O’Connor MJ, Nicolella DP, Enoka RM, Boyan BD, Hart DA,
    Resnick E, Kwoh CK, Tosi LL, Coutts RD, Kohrt WM. Neural and psychosocial
    contributions to sex differences in knee osteoarthritic pain. Biol Sex Differ.
    2012 Dec 17;3(1):26. [Epub ahead of print] PubMed PMID: 23244577.
  • Gittens RA, Olivares-Navarrete R, Cheng A, Anderson DM, McLachlan T, Stephan
    I, Geis-Gerstorfer J, Sandhage KH, Fedorov AG, Rupp F, Boyan BD, Tannenbaum R,
    Schwartz Z. The roles of titanium surface micro/nanotopography and wettability on
    the differential response of human osteoblast lineage cells. Acta Biomater. 2012
    Dec 8. doi:pii: S1742-7061(12)00586-7. 10.1016/j.actbio.2012.12.002. [Epub ahead
    of print] PubMed PMID: 23232211.
  • Gittens RA, Olivares-Navarrete R, McLachlan T, Cai Y, Hyzy SL, Schneider JM,
    Schwartz Z, Sandhage KH, Boyan BD. Differential responses of osteoblast lineage
    cells to nanotopographically-modified, microroughened titanium-aluminum-vanadium
    alloy surfaces. Biomaterials. 2012 Dec;33(35):8986-94. doi:
    10.1016/j.biomaterials.2012.08.059. Epub 2012 Sep 16. PubMed PMID: 22989383.
  • Erdman CP, Dosier CR, Olivares-Navarrete R, Baile C, Guldberg RE, Schwartz Z,
    Boyan BD. Effects of resveratrol on enrichment of adipose-derived stem cells and
    their differentiation to osteoblasts in two-and three-dimensional cultures. J
    Tissue Eng Regen Med. 2012 Dec;6 Suppl 3:s34-46. doi: 10.1002/term.513. Epub 2012
    Mar 30. PubMed PMID: 22467433.
  • Wang Y, Huang YC, Gertzman AA, Xie L, Nizkorodov A, Hyzy SL, Truncale K,
    Guldberg RE, Schwartz Z, Boyan BD. Endogenous regeneration of critical-size
    chondral defects in immunocompromised rat xiphoid cartilage using decellularized
    human bone matrix scaffolds. Tissue Eng Part A. 2012 Nov;18(21-22):2332-42. doi:
    10.1089/ten.TEA.2011.0688. Epub 2012 Jul 30. PubMed PMID: 22731693.
  • Hyzy SL, Olivares-Navarrete R, Hutton DL, Tan C, Boyan BD, Schwartz Z.
    Microstructured titanium regulates interleukin production by osteoblasts, an
    effect modulated by exogenous BMP-2. Acta Biomater. 2012 Oct 31. doi:pii:
    S1742-7061(12)00522-3. 10.1016/j.actbio.2012.10.030. [Epub ahead of print] PubMed
    PMID: 23123301.
  • Park JH, Wasilewski CE, Almodovar N, Olivares-Navarrete R, Boyan BD,
    Tannenbaum R, Schwartz Z. The responses to surface wettability gradients induced
    by chitosan nanofilms on microtextured titanium mediated by specific integrin
    receptors. Biomaterials. 2012 Oct;33(30):7386-93. doi:
    10.1016/j.biomaterials.2012.06.066. Epub 2012 Jul 24. PubMed PMID: 22835642.
  • Hermann CD, Lee CS, Gadepalli S, Lawrence KA, Richards MA, Olivares-Navarrete
    R, Williams JK, Schwartz Z, Boyan BD. Interrelationship of cranial suture fusion,
    basicranial development, and resynostosis following suturectomy in twist1(+/-)
    mice, a murine model of saethre-chotzen syndrome. Calcif Tissue Int. 2012
    Oct;91(4):255-66. doi: 10.1007/s00223-012-9632-3. Epub 2012 Aug 18. PubMed PMID:
    22903506.
  • Boyan BD, Tosi L, Coutts R, Enoka R, Hart DA, Nicolella DP, Berkley K, Sluka
    K, Kwoh K, O’Connor MI, Kohrt W. Sex differences in osteoarthritis of the knee. J
    Am Acad Orthop Surg. 2012 Oct;20(10):668-9. doi: 10.5435/JAAOS-20-10-668. Review.
    PubMed PMID: 23027696.
  • Hyzy SL, Olivares-Navarrete R, Schwartz Z, Boyan BD. BMP2 induces osteoblast
    apoptosis in a maturation state and noggin-dependent manner. J Cell Biochem. 2012
    Oct;113(10):3236-45. doi: 10.1002/jcb.24201. PubMed PMID: 22628200.
  • Doroudi M, Schwartz Z, Boyan BD. Phospholipase A2 activating protein is
    required for 1α,25-dihydroxyvitamin D3 dependent rapid activation of protein
    kinase C via Pdia3. J Steroid Biochem Mol Biol. 2012 Oct;132(1-2):48-56. doi:
    10.1016/j.jsbmb.2012.03.001. Epub 2012 Mar 16. PubMed PMID: 22484374.
  • ElBaradie K, Wang Y, Boyan BD, Schwartz Z. Rapid membrane responses to
    dihydrotestosterone are sex dependent in growth plate chondrocytes. J Steroid
    Biochem Mol Biol. 2012 Oct;132(1-2):15-23. doi: 10.1016/j.jsbmb.2011.12.009. Epub
    2011 Dec 23. PubMed PMID: 22207084.
  • Lee CS, Burnsed OA, Raghuram V, Kalisvaart J, Boyan BD, Schwartz Z. Adipose
    stem cells can secrete angiogenic factors that inhibit hyaline cartilage
    regeneration. Stem Cell Res Ther. 2012 Aug 24;3(4):35. [Epub ahead of print]
    PubMed PMID: 22920724.
  • Olivares-Navarrete R, Raines AL, Hyzy SL, Park JH, Hutton DL, Cochran DL,
    Boyan BD, Schwartz Z. Osteoblast maturation and new bone formation in response to titanium implant surface features are reduced with age. J Bone Miner Res. 2012
    Aug;27(8):1773-83. doi: 10.1002/jbmr.1628. PubMed PMID: 22492532.
  • Boyan BD, Chen J, Schwartz Z. Mechanism of Pdia3-dependent 1Œ±,25-dihydroxy
    vitamin D3 signaling in musculoskeletal cells. Steroids. 2012 Aug;77(10):892-6.
    doi: 10.1016/j.steroids.2012.04.018. Epub 2012 May 5. Review. PubMed PMID:
    22569272.
  • Hermann CD, Richards MA, Olivares-Navarrete R, Williams JK, Guldberg RE,
    Skrinjar O, Schwartz Z, Boyan BD. Algorithm to assess cranial suture fusion with
    varying and discontinuous mineral density. Ann Biomed Eng. 2012
    Jul;40(7):1597-609. doi: 10.1007/s10439-012-0520-9. Epub 2012 Feb 14. PubMed
    PMID: 22350663.
  • Park JH, Olivares-Navarrete R, Wasilewski CE, Boyan BD, Tannenbaum R,
    Schwartz Z. Use of polyelectrolyte thin films to modulate osteoblast response to
    microstructured titanium surfaces. Biomaterials. 2012 Jul;33(21):5267-77. doi:
    10.1016/j.biomaterials.2012.03.074. Epub 2012 Apr 27. PubMed PMID: 22541354.
  • Baker MI, Walsh SP, Schwartz Z, Boyan BD. A review of polyvinyl alcohol and
    its uses in cartilage and orthopedic applications. J Biomed Mater Res B Appl
    Biomater. 2012 Jul;100(5):1451-7. doi: 10.1002/jbm.b.32694. Epub 2012 Apr 19.
    Review. PubMed PMID: 22514196.
  • Dosier CR, Erdman CP, Park JH, Schwartz Z, Boyan BD, Guldberg RE. Resveratrol
    effect on osteogenic differentiation of rat and human adipose derived stem cells
    in a 3-D culture environment. J Mech Behav Biomed Mater. 2012 Jul;11:112-22. doi:
    10.1016/j.jmbbm.2011.08.014. Epub 2011 Aug 31. PubMed PMID: 22658160; PubMed
    Central PMCID: PMC3367162.
  • Olivares-Navarrete R, Sutha K, Hyzy SL, Hutton DL, Schwartz Z, McDevitt T,
    Boyan BD. Osteogenic differentiation of stem cells alters vitamin D receptor
    expression. Stem Cells Dev. 2012 Jul 1;21(10):1726-35. doi:
    10.1089/scd.2011.0411. Epub 2012 Jan 4. PubMed PMID: 22034957; PubMed Central
    PMCID: PMC3376455.
  • Park JH, Olivares-Navarrete R, Baier RE, Meyer AE, Tannenbaum R, Boyan BD,
    Schwartz Z. Effect of cleaning and sterilization on titanium implant surface
    properties and cellular response. Acta Biomater. 2012 May;8(5):1966-75. doi:
    10.1016/j.actbio.2011.11.026. Epub 2011 Dec 2. PubMed PMID: 22154860.
  • Chaudhri RA, Olivares-Navarrete R, Cuenca N, Hadadi A, Boyan BD, Schwartz Z.
    Membrane estrogen signaling enhances tumorigenesis and metastatic potential of
    breast cancer cells via estrogen receptor-α36 (ERα36). J Biol Chem. 2012 Mar
    2;287(10):7169-81. doi: 10.1074/jbc.M111.292946. Epub 2012 Jan 13. PubMed PMID:22247547; PubMed Central PMCID: PMC3293594.
  • Almaguer-Flores A, Olivares-Navarrete R, Wieland M, Xim√©nez-Fyvie LA,
    Schwartz Z, Boyan BD. Influence of topography and hydrophilicity on initial oral
    biofilm formation on microstructured titanium surfaces in vitro. Clin Oral
    Implants Res. 2012 Mar;23(3):301-7. doi: 10.1111/j.1600-0501.2011.02184.x. Epub
    2011 Apr 15. PubMed PMID: 21492236.
  • Olivares-Navarrete R, Gittens RA, Schneider JM, Hyzy SL, Haithcock DA,
    Ullrich PF, Schwartz Z, Boyan BD. Osteoblasts exhibit a more differentiated
    phenotype and increased bone morphogenetic protein production on titanium alloy
    substrates than on poly-ether-ether-ketone. Spine J. 2012 Mar;12(3):265-72. doi:
    10.1016/j.spinee.2012.02.002. Epub 2012 Mar 15. PubMed PMID: 22424980.
  • Wang X, Gittens RA, Song R, Tannenbaum R, Olivares-Navarrete R, Schwartz Z,
    Chen H, Boyan BD. Effects of structural properties of electrospun TiO2 nanofiber
    meshes on their osteogenic potential. Acta Biomater. 2012 Feb;8(2):878-85. doi:
    10.1016/j.actbio.2011.10.023. Epub 2011 Oct 31. PubMed PMID: 22075122; PubMed
    Central PMCID: PMC3309709.
  • Schwartz Z, Hyzy SL, Moore MA, Hunter SA, Ronholdt CJ, Sunwoo M, Boyan BD.
    Osteoinductivity of demineralized bone matrix is independent of donor
    bisphosphonate use. J Bone Joint Surg Am. 2011 Dec 21;93(24):2278-86. doi:
    10.2106/JBJS.J.01469. PubMed PMID: 22258774; PubMed Central PMCID: PMC3234347.
  • Gittens RA, Olivares-Navarrete R, Tannenbaum R, Boyan BD, Schwartz Z.
    Electrical implications of corrosion for osseointegration of titanium implants. J
    Dent Res. 2011 Dec;90(12):1389-97. doi: 10.1177/0022034511408428. Epub 2011 May
    9. Review. PubMed PMID: 21555775; PubMed Central PMCID: PMC3215755.
  • Olivares-Navarrete R, Hyzy SL, Park JH, Dunn GR, Haithcock DA, Wasilewski CE,
    Boyan BD, Schwartz Z. Mediation of osteogenic differentiation of human
    mesenchymal stem cells on titanium surfaces by a Wnt-integrin feedback loop.
    Biomaterials. 2011 Sep;32(27):6399-411. doi: 10.1016/j.biomaterials.2011.05.036.
    Epub 2011 Jun 1. PubMed PMID: 21636130; PubMed Central PMCID: PMC3350791.
  • Lee CS, Chen J, Wang Y, Williams JK, Ranly DM, Schwartz Z, Boyan BD.
    Coordinated tether formation in anatomically distinct mice growth centers is
    dependent on a functional vitamin D receptor and is tightly linked to
    three-dimensional tissue morphology. Bone. 2011 Sep;49(3):419-27. doi:
    10.1016/j.bone.2011.05.004. Epub 2011 May 11. PubMed PMID: 21601024.
  • Bell BF, Schuler M, Tosatti S, Textor M, Schwartz Z, Boyan BD. Osteoblast
    response to titanium surfaces functionalized with extracellular matrix peptide
    biomimetics. Clin Oral Implants Res. 2011 Aug;22(8):865-72. doi:
    10.1111/j.1600-0501.2010.02074.x. Epub 2011 Jan 18. PubMed PMID: 21244501.
  • Olivares-Navarrete R, Hyzy SL, Hutton DL, Dunn GR, Appert C, Boyan BD,
    Schwartz Z. Role of non-canonical Wnt signaling in osteoblast maturation on
    microstructured titanium surfaces. Acta Biomater. 2011 Jun;7(6):2740-50. doi:
    10.1016/j.actbio.2011.02.030. Epub 2011 Feb 23. PubMed PMID: 21352958.
  • Stephens DS, West AC, Ofili EO, Boyan BD, Blumberg HM. The Atlanta Clinical
    and Translational Science Institute: clinical and translational science education
    and training partnership. Clin Transl Sci. 2011 Jun;4(3):143-5. doi:
    10.1111/j.1752-8062.2011.00293.x. PubMed PMID: 21707942; PubMed Central PMCID:
    PMC3125607.
  • Park JH, Schwartz Z, Olivares-Navarrete R, Boyan BD, Tannenbaum R.
    Enhancement of surface wettability via the modification of microtextured titanium
    implant surfaces with polyelectrolytes. Langmuir. 2011 May 17;27(10):5976-85.
    doi: 10.1021/la2000415. Epub 2011 Apr 22. PubMed PMID: 21513319.
  • Gittens RA, McLachlan T, Olivares-Navarrete R, Cai Y, Berner S, Tannenbaum R,
    Schwartz Z, Sandhage KH, Boyan BD. The effects of combined
    micron-/submicron-scale surface roughness and nanoscale features on cell
    proliferation and differentiation. Biomaterials. 2011 May;32(13):3395-403. doi:
    10.1016/j.biomaterials.2011.01.029. PubMed PMID: 21310480; PubMed Central PMCID:
    PMC3350795.
  • Kou PM, Schwartz Z, Boyan BD, Babensee JE. Dendritic cell responses to
    surface properties of clinical titanium surfaces. Acta Biomater. 2011
    Mar;7(3):1354-63. doi: 10.1016/j.actbio.2010.10.020. Epub 2010 Oct 25. PubMed
    PMID: 20977948; PubMed Central PMCID: PMC3031747.
  • Singh K, Moyer H, Williams JK, Schwartz Z, Boyan BD. Fibrin glue: a scaffold
    for cellular-based therapy in a critical-sized defect. Ann Plast Surg. 2011
    Mar;66(3):301-5. doi: 10.1097/SAP.0b013e3181fc0507. PubMed PMID: 21263290.
  • Raines AL, Sunwoo M, Gertzman AA, Thacker K, Guldberg RE, Schwartz Z, Boyan
    BD. Hyaluronic acid stimulates neovascularization during the regeneration of bone
    marrow after ablation. J Biomed Mater Res A. 2011 Mar 1;96(3):575-83. doi:
    10.1002/jbm.a.33012. Epub 2011 Jan 10. PubMed PMID: 21254389.
  • Zhong M, Carney DH, Jo H, Boyan BD, Schwartz Z. Inorganic phosphate induces
    mammalian growth plate chondrocyte apoptosis in a mitochondrial pathway involving
    nitric oxide and JNK MAP kinase. Calcif Tissue Int. 2011 Feb;88(2):96-108. doi:
    10.1007/s00223-010-9433-5. Epub 2010 Nov 23. PubMed PMID: 21104071.
  • Raines AL, Sunwoo M, Gertzman AA, Thacker K, Guldberg RE, Schwartz Z, Boyan
    BD. Hyaluronic acid stimulates neovascularization during the regeneration of bone
    marrow after ablation. J Biomed Mater Res A. 2011 Jan 10. [Epub ahead of print]
    PubMed PMID: 21225712.
  • Zhong M, Carney DH, Boyan BD, Schwartz Z. 17Œ≤-Estradiol regulates rat growth
    plate chondrocyte apoptosis through a mitochondrial pathway not involving nitric
    oxide or MAPKs. Endocrinology. 2011 Jan;152(1):82-92. doi: 10.1210/en.2010-0509. Epub 2010 Nov 10. PubMed PMID: 21068162.
  • Boyan BD, Schwartz Z. Regenerative medicine: Are calcium phosphate ceramics
    ‘smart’ biomaterials? Nat Rev Rheumatol. 2011 Jan;7(1):8-9. doi:
    10.1038/nrrheum.2010.210. PubMed PMID: 21206482.
  • Chen J, Olivares-Navarrete R, Wang Y, Herman TR, Boyan BD, Schwartz Z.
    Protein-disulfide isomerase-associated 3 (Pdia3) mediates the membrane response
    to 1,25-dihydroxyvitamin D3 in osteoblasts. J Biol Chem. 2010 Nov
    19;285(47):37041-50. doi: 10.1074/jbc.M110.157115. Epub 2010 Sep 15. PubMed PMID:
    20843786; PubMed Central PMCID: PMC2978632.
  • Olivares-Navarrete R, Hyzy SL, Chaudhri RA, Zhao G, Boyan BD, Schwartz Z. Sex
    dependent regulation of osteoblast response to implant surface properties by
    systemic hormones. Biol Sex Differ. 2010 Nov 4;1(1):4. doi:
    10.1186/2042-6410-1-4. PubMed PMID: 21208469; PubMed Central PMCID: PMC3010104.
  • Moyer HR, Kinney RC, Singh KA, Williams JK, Schwartz Z, Boyan BD. Alginate
    microencapsulation technology for the percutaneous delivery of adipose-derived
    stem cells. Ann Plast Surg. 2010 Nov;65(5):497-503. doi:
    10.1097/SAP.0b013e3181d37713. PubMed PMID: 20842001.
  • Lennon FE, Hermann CD, Olivares-Navarrete R, Rhee WJ, Schwartz Z, Bao G,
    Boyan BD. Use of molecular beacons to image effects of titanium surface
    microstructure on beta1 integrin expression in live osteoblast-like cells.
    Biomaterials. 2010 Oct;31(30):7640-7. doi: 10.1016/j.biomaterials.2010.07.009.
    Epub 2010 Jul 31. PubMed PMID: 20674005; PubMed Central PMCID: PMC3350792.
  • Hurst-Kennedy J, Zhong M, Gupta V, Boyan BD, Schwartz Z.
    24R,25-Dihydroxyvitamin D3, lysophosphatidic acid, and p53: a signaling axis in
    the inhibition of phosphate-induced chondrocyte apoptosis. J Steroid Biochem Mol
    Biol. 2010 Oct;122(4):264-71. doi: 10.1016/j.jsbmb.2010.05.010. Epub 2010 Jun 8.
    PubMed PMID: 20594980.
  • Smith KE, Hyzy SL, Sunwoo M, Gall KA, Schwartz Z, Boyan BD. The dependence of
    MG63 osteoblast responses to (meth)acrylate-based networks on chemical structure and stiffness. Biomaterials. 2010 Aug;31(24):6131-41. doi:
    10.1016/j.biomaterials.2010.04.033. Epub 2010 May 26. PubMed PMID: 20510445;
    PubMed Central PMCID: PMC2896827.
  • Wang Y, Chen J, Lee CS, Nizkorodov A, Riemenschneider K, Martin D, Hyzy S,
    Schwartz Z, Boyan BD. Disruption of Pdia3 gene results in bone abnormality and
    affects 1alpha,25-dihydroxy-vitamin D3-induced rapid activation of PKC. J Steroid
    Biochem Mol Biol. 2010 Jul;121(1-2):257-60. doi: 10.1016/j.jsbmb.2010.05.004.
    Epub 2010 May 16. PubMed PMID: 20576531.
  • Boyan BD, Hurst-Kennedy J, Denison TA, Schwartz Z. 24R,25-dihydroxyvitamin D3
    [24R,25(OH)2D3] controls growth plate development by inhibiting apoptosis in the
    reserve zone and stimulating response to 1alpha,25(OH)2D3 in hypertrophic cells.
    J Steroid Biochem Mol Biol. 2010 Jul;121(1-2):212-6. doi:
    10.1016/j.jsbmb.2010.03.057. Epub 2010 Mar 20. PubMed PMID: 20307662.
  • Moyer HR, Wang Y, Farooque T, Wick T, Singh KA, Xie L, Guldberg RE, Williams
    JK, Boyan BD, Schwartz Z. A new animal model for assessing cartilage repair and
    regeneration at a nonarticular site. Tissue Eng Part A. 2010 Jul;16(7):2321-30.
    doi: 10.1089/ten.TEA.2009.0245. PubMed PMID: 20192719.
  • Lee CS, Moyer HR, Gittens RA, Williams JK, Boskey AL, Boyan BD, Schwartz Z.
    Regulating in vivo calcification of alginate microbeads. Biomaterials. 2010
    Jun;31(18):4926-34. doi: 10.1016/j.biomaterials.2010.03.001. Epub 2010 Apr 2.
    PubMed PMID: 20363022; PubMed Central PMCID: PMC3358131.
  • Raines AL, Olivares-Navarrete R, Wieland M, Cochran DL, Schwartz Z, Boyan BD.
    Regulation of angiogenesis during osseointegration by titanium surface
    microstructure and energy. Biomaterials. 2010 Jun;31(18):4909-17. doi:
    10.1016/j.biomaterials.2010.02.071. Epub 2010 Mar 30. PubMed PMID: 20356623;
    PubMed Central PMCID: PMC2896824.
  • Wang Y, Bella E, Lee CS, Migliaresi C, Pelcastre L, Schwartz Z, Boyan BD,
    Motta A. The synergistic effects of 3-D porous silk fibroin matrix scaffold
    properties and hydrodynamic environment in cartilage tissue regeneration.
    Biomaterials. 2010 Jun;31(17):4672-81. doi: 10.1016/j.biomaterials.2010.02.006.
    Epub 2010 Mar 19. PubMed PMID: 20303584.
  • Coleman RM, Phillips JE, Lin A, Schwartz Z, Boyan BD, Guldberg RE.
    Characterization of a small animal growth plate injury model using microcomputed
    tomography. Bone. 2010 Jun;46(6):1555-63. doi: 10.1016/j.bone.2010.02.017. Epub
    2010 Feb 20. PubMed PMID: 20176156.
  • Fang M, Olivares-Navarrete R, Wieland M, Cochran DL, Boyan BD, Schwartz Z.
    The role of phospholipase D in osteoblast response to titanium surface
    microstructure. J Biomed Mater Res A. 2010 Jun 1;93(3):897-909. doi:
    10.1002/jbm.a.32596. PubMed PMID: 19705469.
  • Bairey Merz CN, Mark S, Boyan BD, Jacobs AK, Shah PK, Shaw LJ, Taylor D,
    Marb√°n E. Proceedings from the scientific symposium: Sex differences in
    cardiovascular disease and implications for therapies. J Womens Health (Larchmt).
    2010 Jun;19(6):1059-72. doi: 10.1089/jwh.2009.1695. PubMed PMID: 20500123; PubMed Central PMCID: PMC2940456.
  • Olivares-Navarrete R, Hyzy SL, Hutton DL, Erdman CP, Wieland M, Boyan BD,
    Schwartz Z. Direct and indirect effects of microstructured titanium substrates on
    the induction of mesenchymal stem cell differentiation towards the osteoblast
    lineage. Biomaterials. 2010 Apr;31(10):2728-35. doi:
    10.1016/j.biomaterials.2009.12.029. Epub 2010 Jan 6. PubMed PMID: 20053436;
    PubMed Central PMCID: PMC2821717.
  • Olivares-Navarrete R, Hyzy S, Wieland M, Boyan BD, Schwartz Z. The roles of
    Wnt signaling modulators Dickkopf-1 (Dkk1) and Dickkopf-2 (Dkk2) and cell
    maturation state in osteogenesis on microstructured titanium surfaces.
    Biomaterials. 2010 Mar;31(8):2015-24. doi: 10.1016/j.biomaterials.2009.11.071.
    Epub 2009 Dec 9. PubMed PMID: 20004015.
  • Fisher M, Hyzy S, Guldberg RE, Schwartz Z, Boyan BD. Regeneration of bone
    marrow after tibial ablation in immunocompromised rats is age dependent. Bone.
    2010 Feb;46(2):396-401. doi: 10.1016/j.bone.2009.09.029. Epub 2009 Sep 30. PubMed PMID: 19800046.