Virginia Commonwealth University
VCU Engineering
liquid

Dr. Gary L. Bowlin

Associate Professor, Department of Biomedical Engineering
Harris Exceptional Scholar Professorship
Assistant Chair/Graduate Coordinator
Director, Tissue Engineering Laboratory
E-mail: glbowlin@vcu.edu
Phone: (804) 828-2592
Fax: (804) 828-4454
Website: http://www.people.vcu.edu/%7Eglbowlin
Dr. Gary L. Bowlin

Address

Virginia Commonwealth University
School of Engineering
Department of Biomedical Engineering
East Hall, Room E1254
401 W. Main St
P.O. Box 843067
Richmond, Virginia 23284-3067

Books and/or Chapters

  • Editor: "Encyclopedia of Biomaterials and Biomedical Engineering" (G.E. Wnek, Co-editor) Marcel Dekker, Inc., New York, N.Y. Expected Publication: Early 2004.
  • Boland, E.D.; Espy, P. and G.L. Bowlin. "Tissue Engineering Scaffolds." In Encyclopedia of Biomaterials and Biomedical Engineering. G.E. Wnek and G.L. Bowlin, Eds., Marcel Dekker, N.Y., In Press.
  • Boland, E.D.; Wnek, G.E. and G.L. Bowlin. "Poly(Gylcolic Acid)" In Encyclopedia of Biomaterials and Biomedical Engineering. G.E. Wnek and G.L. Bowlin, Eds., Marcel Dekker, N.Y., In Press.
  • Bowlin, G.L., Pawlowski, K.J., Stitzel, J.D., Boland, E.D., Simpson, D.G., Fenn, J.B. and G.E. Wnek. "Electrospinning of Polymer Scaffolds for Tissue Engineering." In Tissue Engineering and Biodegradable Equivalents: Scientific and Clinical Applications. K. Lewandrowsky, D. J. Trantolo, J. D. Gresser, M. J. Yaszemski, D. E. Altobelli and D. L. Wise, Eds, Marcel Dekker, N.Y., Chapter 9: 65-178: 2002.
  • Bowlin, G.L. Schmidt, S.P., Rittgers, S.E., and K.J. Pawlowski. "Endothelialization of Vascular Prostheses." In Biomaterials Engineering & Devices: Human Applications. D. Wise, et al., Eds. The Humana Press, Inc., Chapter 6: 85-118: 2000.
  • Schmidt, S.P. and G.L. Bowlin. "Endothelial Cell Seeding: A Review." In Tissue Engineering of Prosthetic Vascular Grafts. P.P. Zilla and H.P. Greisler, Eds. Academic Press, Chapter 3: 61-68; 1997.

Classes Taught

  • Senior Design Studio (udergraduate)
  • Vascular Prosthetic Tissue Engineering (graduate)
  • Tissue Engineering (graduate)
  • Biomaterials (graduate and undergraduate)

Current Projects

  • Determine industrial chemical exposure limits
  • Biological/chemical warfare agent detection
  • Tissue-based biosensor
  • Nerve guides
  • Muscle implants
  • Small diameter vascular grafts
  • Novel production of tissue engineering scaffolds (< 10 micron fibers and/or beads)
  • Muscle tissue engineering (skeletal and cardiac)
  • Development of a small diameter biomimicking (tissue engineered) vascular prosthesis
  • In vivo insulin delivery system
  • Gene therapy
  • Intravascular stents
  • Small diameter vascular prostheses
  • Simultaneous electrostatic endothelial cell transplantation/transfection
  • Intravascular stents
  • Small diameter vascular prostheses and endovascular grafts
  • Electrostatic endothelial cell transplantation

Education

  • B.S. Chemical Engineering, Youngstown State University, 1988
  • M.S. Chemical Engineering, University of New Hampshire, 1990
  • Ph.D. Biomedical Engineering, The University of Akron, 1996

Patents

  • U.S. Patent # 6,010,573: "Apparatus and Method for Electrostatic Endothelial Cell Seeding and DNA Transfection of Intravascular Stents." Bowlin, G.L., Virginia Commonwealth University. Issued: January 4, 2000
  • U.S. Patent # 5,723,324: "Apparatus and Method for Electrostatic Endothelial Cell Seeding and DNA Transfection in a Vascular Prosthesis." Bowlin, G.L. and S.E. Rittgers, The University of Akron. Issued: March 3, 1998
  • U.S. Patent # 5,714,359: "Electrostatic Endothelial Cell Seeding: Apparatus and Procedure." Bowlin, G.L. and S.E. Rittgers, The University of Akron. Issued: February 3, 1998

Publications

  • Bowlin, G.L. and S.E. Rittgers. "A Prototype Apparatus and Procedure for Electrostatic Endothelial Cell Transplantation within Small Diameter (< 6 mm) Vascular Prostheses." Cell Transplantation 6: 631-7, 1997. search for publication
  • Bowlin, G.L. and S.E. Rittgers. "Electrostatic Endothelial Cell Seeding of Small Diameter (< 6 mm) Vascular Prostheses: Feasibility Study." Cell Transplantation 6: 623-9, 1997. search for publication
  • Bowlin, G.L.; Rittgers, S.E.; Milsted, A.; and Schmidt, S.P. "In Vitro Evaluation of Electrostatic Endothelial Cell Transplantation onto 4 mm I.D. e-PTFE Grafts." J. Vasc. Surg., 27: 504-11, 1998. search for publication
  • Bowlin, G.L.; Rittgers, S.E.; Schmidt, S.P.; Alexander, T.; Sheffer, D.B.; and Milsted, A. "Optimization of an Electrostatic Endothelial Cell Transplantation Technique Using 4 mm I.D. e-PTFE Vascular Prostheses." Cell Transplantation, 9: 337-48, 2000. search for publication
  • Stitzel, J.D.; Pawlowski, K.J.; Wnek, G.E.; Simpson, D.G.; Bowlin, G.L.. "Arterial Smooth Muscle Cell Proliferation on a Novel Biomimicking, Biodegradable Vascular Graft Scaffold." J. Biomaterials Applications, 15: 1-12, 2001. search for publication
  • Fields, C.; Cassano, A.; Allen, C.; Meyer, A.; Rittgers, S.E.; Makhoul, R.G. and G.L. Bowlin. "The Persistence of Electrostatically Seeded Endothelial Cells Lining a Small Diameter Expanded Polytetrafluoroethylene Vascular Graft." J. Biomaterials Applications, 16: 157-73, 2001. search for publication
  • Fields, C.; Cassano, A.; Allen, C.; Sims, R.; Bulgrin, J.; Meyer, A.; Makhoul, R.G.; Rittgers, S.E.; and G.L. Bowlin. "Evaluation of Electrostatically Endothelial Cell Seeded Expanded Polytetrafluoroethylene Grafts in a Canine Femoral Artery Model." J. Biomaterials Applications, 17 (2): 135-154, 2002. search for publication
  • Kenawy, E.; Mansfield, K.; Bowlin, G.L.; Simpson, D.G.; and G.E. Wnek. "New Drug Delivery System: Control Release of Tetracycline Hydrochloride as a Model Drug from Electrospun Fibers of Poly(lactic acid) and Poly(ethylene vinyl acetate)." J. Control Release, 81(1,2): 57-64, 2002. search for publication
  • Matthews, J.A.; Simpson, D.G.; Wnek, G.E.; and G.L. Bowlin. "Electrospinning of Collagen Nanofibers." Biomacromolecules, 3 (2): 232-238, 2002. search for publication
  • Boland, E.D.; Wnek, G.E.; Simpson, D.G.; Pawlowski, K.J. and G.L. Bowlin. "Tailoring Tissue Engineering Scaffolds Using Electrostatic Processing Techniques: A Study of Poly(Glycolic Acid)." J. Macromol. Sci., 38: 1231-43, 2001. search for publication
  • Fields, C.; Cassano, A.; Allen, C.; Meyer, A.; Rittgers, S.E.; Szycher, M.; Pawlowski, K.J.; and G.L. Bowlin. "Endothelial Cell Seeding of a 4-mm I.D. Polyurethane Vascular Graft." J. Biomaterials Applications, 17(1): 45-70, 2002. search for publication
  • Kenawy, E.; Layman, J.; Matthews, J.A.; Bowlin, G.L.; Simpson, D.G.; and G.E. Wnek. "Electrospinning of Poly(Ethylene-co-Vinyl Alcohol) Fibers." Biomaterials, 24: 907-13, 2003. search for publication
  • G.L. Bowlin. "Electrospinning Collagen Scaffolds." Science and Medicine, 8: 292-93, November/December 2002. search for publication
  • Matthews, J.A.; Boland, E.D.; Wnek, G.E.; Simpson, D.G.; and G.L. Bowlin. "Electrospinning of Collagen Type II: A Feasibility Study." J. Bioactive and Compatible Polymers, 18, 125-34, 2003. search for publication
  • Wnek, G.E.; Carr, M.E.; Simpson, D.G.; and G.L. Bowlin."Electrospinning of Nanofiber Fibrinogen Structures." Nano Letters, 3(2): 213-16, 2003. search for publication
  • Yao, L.; Haas, T.W.; Guiseppi-Elie, A.; Bowlin, G.L.; Simpson, D.G.; and G.E. Wnek. "Electrospinning and Stabilization of Fully Hydrolyzed Poly(vinyl alcohol) Fibers." Chemistry of Materials, 15, 1860-64, 2003. search for publication
  • Sanders, E.H.; Kloefkorn, R.; Bowlin, G.L.; Simpson, D.G.; and G.E. Wnek. "Two-Phase Electrospinning from a Single Electrified Jet: Microencapsulation of Aqueous Reservoirs in Poly(Ethylene-co-Vinyl Acetate) Fibers." Macromolecules, 36, 3803-5, 2003. search for publication
  • Pawlowski, K.J., Boland, E.D., Simpson, D.G., Wnek, G.E. and G.L. Bowlin. "Electrospinning: A Revitalized Polymer Processing Technique." J. of Chemical Education, In Preparation. search for publication

Research Topics

  • Electrostatic endothelial cell seeding techniques and transplantation/transfection
  • Development of novel tissue engineering scaffolds via electrospinning
Our vision
dream it. think it. do it.
Virginia Commonwealth University | School of Engineering
601 West Main Street | P.O. Box 843068 | Richmond, Virginia 23284-3068
Phone: (804) 828-3925 | TDD: (800) 828-1120 | Fax: (804) 828-9866 | E-mail: askengineering@vcu.edu
Last Update: 11/22/2009 4:59:46 PM | Maintained by Web Coordinator