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Book Chapters

• Kleinstreuer, C. and Longest, P. W. 2003. Particle-hemodynamics analyses of end-to-side anastomoses: A computational comparison study. In: Vascular Grafts – Experiment and Modeling, A. Tura (ed.), WIT Press, Ashurst, UK.

Classes Taught

• EGRM 661/ENGR 591 Computational Fluid Dynamics
• EGRM 561/ENGR 691 Advanced Fluid Mechanics
• ENGR 301 Fluid Mechanics

Education

• B.S. in Mechanical Engineering, North Carolina State University, Raleigh, NC, 1996
• M.S. in Mechanical Engineering, North Carolina State University, Raleigh, NC, 1999
• Ph.D. in Mechanical Engineering, North Carolina State University, Raleigh, NC, 2002

Journal Publications

• Buchanan, C. D., Kleinstreuer, C., and Longest, P. W. 1998. Analytical solution to flux enhancement in laminar concentrically stratified pipe flow of Bingham and Newtonian fluids. Journal of Fluids Engineering. 120(3): 629-631.
• Longest, P. W., Kleinstreuer, C., and Kinsey, J. S. 1998. Turbulent three-dimensional air flow and trace gas distribution in an inhalation test chamber. Journal of Fluids Engineering. 122:403-411.
• Longest, P. W., Kleinstreuer, C., and Andreotti, P. J. 2000. Computational analysis and design improvements of graft-to-vein anastomoses. Critical Reviews in Biomedical Engineering. 28(1&2):141-147.
• Longest, P. W. and Kleinstreuer, C. 2000. Computational analysis and comparison study of arterio-venous grafts.  Journal of Medical Engineering and Technology. 24(3):102-110.
• Kleinstreuer, C., Hyun, S., Buchanan, J. R., Longest, P. W., Archie, J. P., and Truskey, G. A. 2001. Hemodynamic parameters and early intimal thickening in branching blood vessels.  Critical Reviews in Biomedical Engineering. 29(1):1-64.
• Longest, P. W., Kleinstreuer, C., and Buchanan, J. R. 2001. A new near-wall residence time model applied to three arterio-venous graft end-to-side anastomoses. Computer Methods in Biomechanics and Biomedical Engineering. 4:379-397.
• Longest, P. W. and Kleinstreuer, C. 2003. Particle hemodynamics of the distal end-to-side femoral bypass: Effects of graft caliber and graft-end cut. Medical Engineering and Physics. 25:843-858.
• Longest, P. W., Kleinstreuer, C., and Archie, J. P. 2003. Particle-hemodynamics analysis of the Miller-cuff arterial anastomosis. Journal of Vascular Surgery. 38:1353-1362.
• Longest, P. W., Kleinstreuer, C., Truskey, G. A., and Buchanan, J. R. 2003. Relation between near-wall residence times of monocytes and early lesion growth in the rabbit aorto-celiac junction.  Annals of Biomedical Engineering. 31:53-64.
• Longest, P. W. and Kleinstreuer, C. 2003. Comparison of blood particle deposition models for non-parallel flow domains.  Journal of Biomechanics. 36:421-430.
• Longest, P. W. and Kleinstreuer, C. 2003. Numerical simulation of wall shear stress conditions and platelet localization in realistic end-to-side arterial anastomoses. ASME Journal of Biomechanical Engineering. 125:671-681.
• Hyun, S., Kleinstreuer, C., and Longest, P. W. 2004. Particle-hemodynamics simulations and design options for surgical reconstruction of diseased carotid artery bifurcations. ASME Journal of Biomechanical Engineering. 126(2):188-195.
• Longest, P. W., Kleinstreuer, C., and Buchanan, J. R. 2004. Efficient computation of micron-particle dynamics including wall effects. Computers and Fluids. 33:577-601.
• Longest, P. W. and Kleinstreuer, C. 2004.  Interacting effects of uniform flow, plane shear, and near-wall proximity on the heat and mass transfer of respiratory aerosols. International Journal of Heat and Mass Transfer. 47:4745-4759.
• Longest, P. W. and Kleinstreuer, C. 2005.  Computational models for simulating multicomponent aerosol evaporation in the upper respiratory airways. Aerosol Science and Technology. 39:124-138.
• Pidaparti, R., Longest, P. W., Hsu, A. T. and Akay, H. U. 2005. Coupled fluid dynamics analysis of an idealized nanoscale bio-molecular motor. Bulletin of the Polish Academy of Sciences – Technical Sciences. 53(4):405-412.
• Longest, P. W., Kleinstreuer, C., Deanda, A. 2005. Numerical simulations of wall shear stress and particle-based hemodynamic parameters in pre-cuffed and streamlined end-to-side anastomoses. Annals of Biomedical Engineering. 33(12):1752-1766.
• Xi, J., Si, X., Longest, P. W. and Gad-el-Hak, M. 2006.  Curvature law of the wall for swirling axial flows in rotating machinery. ASME Journal of Fluids Engineering. (in press).
• Longest, P. W., Vinchurkar, S., and Martonen, T. B. 2006. Transport and deposition of respiratory aerosols in models of childhood asthma. Journal of Aerosol Science. (in press).
• Longest, P. W. and Vinchurkar, S. 2006. Validating CFD predictions of respiratory aerosol deposition: Effects of upstream transition and turbulence. Journal of Biomechanics. (in press).
• Longest, P. W. and Vinchurkar, S. 2006. Effects of mesh style and grid convergence on particle deposition in bifurcating airway models with comparisons to experimental data. Medical Engineering and Physics. (in press).
• Longest, P. W. and Oldham, M. J. 2006. Mutual enhancements of CFD modeling and experimental data: A case study of one micrometer particle deposition in a branching airway model. Inhalation Toxicology. 18(10) 761-772.

Research Experience

• 2002 – 2003
  Post-doctoral Research Fellow, Air Force Office of Scientific Research, conducted at North Carolina State University, Raleigh, NC
• 2003 – 2004
  Post-doctoral Research Fellow, U.S. Environmental Protection Agency, NERL, Exposure Modeling Research Branch, RTP, NC
• 2004 – Present
  Assistant Professor, Department of Mechanical Engineering, Virginia Commonwealth University

Research Topics

• Optimal design of vascular prostheses (grafts and stents)
• Microcirculation transport and thrombosis occlusion models
• Simulating the role of particle hemodynamics in vascular diseases
• Development of next-generation inhalation devices for therapeutic aerosol delivery
• Multiscale modeling of respiratory dosimetry down to the cellular level
• Transport of toxic and therapeutic aerosols and vapors in the respiratory tract
• Multiphase biofluid transport with applications to respiratory and cardiovascular therapies