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Education

• B.S. Chemical Engineering, Worcester Polytechnic Institute, 1998
• M.S. Bioengineering, University of California, San Diego 2001
• Ph.D. Bioengineering, University of California, San Diego, 2004

Recent Publications

• Pazzano D., Mercier K.A., Moran J.M., Fong S.S., DiBiasio D.D., Rulfs J.X., Kohles S.S., Bonassar L.J. 2000. Comparison of chondrogensis in static and perfused bioreactor culture. Biotechnology Progress. 16(5):893-6.
• Lee, G.M., Fong, S., Francis, K., Oh, D.J., Palsson, B.O. 2000. In situ labeling of adherent cells with PKH26. In Vitro Cell and Developmental Biology Animal. 36(1):4-6.
• Lee, G.M., Fong, S.S., Oh, D.J., Francis, K., Palsson, B.O. 2002. Characterization and efficacy of PKH26 as a probe to study the replication history of the human hematopoietic KG1a progenitor cell line. In Vitro Cell and Developmental Biology Animal. 38(2):90-6.
• Francis, K., Palsson B., Donahue, J., Fong, S., Carrier, E. 2002. Murine Sca-1(+)/Lin(-) cells and human KG1a cells exhibit multiple pseudopod morphologies during migration. Experimental Hematology. 30(5):460-3.
• Reed, J.L., Fong, S.S., Palsson, B.O. 2003. “Phenomics” in Microbial Diversity and Bioprospecting ASMPress 2003.
• Fong, S.S., Marciniak, J.Y., Palsson, B.O. 2003. Description and interpretation of adaptive evolution of Escherichia coli K-12 MG1655 by using a genome-scale in silico metabolic model. Journal of Bacteriology. 185(21):6400-8.
• Fong, S.S., Palsson, B.O. 2004. Metabolic gene deletion strains of Escherichia coli evolve to computationally predicted growth phenotypes. Nature Genetics. 36(10):1056-8.
• Fong, S.S., Burgard, A.P., Herring, C.H., Knight, E.M., Blattner, F.R., Maranas, C.D., Palsson, B.O. 2005. In silico design and adaptive evolution of Escherichia coli for production of lactic acid. (Biotechnology & Bioengineering. 91(5): 643-648)
• Fong, S.S., Joyce, A.J., Palsson, B.O. 2005. Parallel adaptive evolution cultures of Escherichia coli lead to convergent, phenotypes with different expression states. (Genome Research. In Press.)
• Fong, S.S.*, Perrenoud, A.*, Palsson, B.O., Sauer, U. 2005. Adaptive evolution of gene deletion strains of Escherichia coli result in novel flux patterns. In preparation.

Research Interests

• Computational modeling
• Molecular evolution
• Molecular engineering
• Metabolic engineering
• Evolutionary biology
• Systems biology